Abstract:The contradiction between generation and being constitutes the underlying logic of practical philosophy, and the relationship between generation and being is the essential issue of practical philosophy. For a long time, the view of being by metaphysics, which serves as the basis of speculating the ontology of metaphysics, has dominated the development of the contradiction between generation and being. Therefore, traditional practical philosophy takes the being of metaphysics as its ultimate goal, and deems practice as the way of transcending the generated phenomenal world and entering the unchanging noumenal world. In the process of rebelling against metaphysics, modern practical philosophy awakens the generating power but falls into nihilism: Schopenhauer believed that human beings, as the finite existence of the representation world, are rooted in the noumenon world of restless will, so they are in the eternal conflict between finite existence and infinite will. Peace can only be achieved through elimination of the will. Nietzsche argues that the metaphysical world is the hypocrisy of the will, a strategy invented by the sick will to power against stronger will. Historical materialism reveals the dialectical interaction between generation and being, providing a possible way to solve the contradiction between generation and being.